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DES has been used to treat estrogen responsive tumors, hyperplasia of the prostate gland and in perianal gland adenomas. However, neutering (castration) is the initial。

Diethylstilbestrol (DES) has only one primary use: the treatment of sphincter tone incontinence in female dogs. DES idiethylstilbestrol for dogs side effectss used at extremely low doses thus avoiding any toxicity。

Other side effects include signs of being in heat, including vaginal discharge or spotting, infection of the uterus in intact female dogs (pyometra), cystic endometrial hyperplasia and other abnormalities of the reproductive system, diarrhea, vomiting, lack of energy,。

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